| 產(chǎn)品編號(hào) | bsm-61433R |
| 英文名稱 | Cathepsin L/V/K/H Recombinant Rabbit mAb |
| 中文名稱 | 組織蛋白酶L/V/K/H重組兔單抗 |
| 別 名 | Cathepsin; CTSL; CTSV; CTSK; CTSH. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Recombinant |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200,Flow-Cyt=1:20-50,ICC/IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 37,38 kDa |
| 檢測(cè)分子量 | 38 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Cathepsin L/V/K/H |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Plays a critical for normal cellular functions such as general protein turnover, antigen processing and bone remodeling. SWISS: P07711 Gene ID: 1514 合成與降解（Synthesis and Degradation） 組織蛋白酶L(cathepsin L CL)屬于木瓜蛋白酶家族中的半胱氨酸蛋白水解酶，以酶原的形式貯存于溶酶體中. 參與許多特殊的生理過(guò)程，如激素原的激活、抗原呈遞、組織器官的發(fā)育等。 在病理狀態(tài)下，因各種原因所致的細(xì)胞損傷(如病原微生物、炎癥因子、氧化應(yīng)激等)可降解細(xì)胞成分或細(xì)胞間質(zhì)基質(zhì)成分，包括層粘素、IV型膠原纖維及纖維連接素等，與人類許多疾病如腫瘤的浸潤(rùn)與轉(zhuǎn)移、關(guān)節(jié)炎、骨質(zhì)疏松、阿爾茨海姆病、多發(fā)性硬化癥及其他慢性炎癥性疾病有關(guān). |
| 產(chǎn)品圖片 |
Western blot analysis of (1) HepG2 cell lysate; (2) NIH/3T3 cell lysate; (3) PC-12 cell lysate; Using Cathepsin L/V/K/H (bsm-61433R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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