| 產(chǎn)品編號 | bsm-61471R |
| 英文名稱 | p53BP1 Recombinant Rabbit mAb |
| 中文名稱 | p53結(jié)合蛋白1重組兔單抗 |
| 別 名 | Tumor suppressor p53-binding protein 1; 53 BP1; p53-binding protein 1; p53BP1; TP53BP1; p53-BP1; p202. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200,Flow-Cyt=1:20-50,ICC/IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 214 kDa |
| 檢測分子量 | 450 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TP53BP1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Plays a key role in the repair of double-strand DNA breaks (DSBs) in response to DNA damage by promoting non-homologous end joining (NHEJ)-mediated repair of DSBs and specifically counteracting the function of the homologous recombination (HR) repair protein BRCA1. SWISS: Q12888 Gene ID: 7158 p53結(jié)合蛋白1(53BP1)是細(xì)胞周期檢查點(diǎn)激酶蛋白，是新近發(fā)現(xiàn)的DNA損傷修復(fù)通路中兩個非常重要的蛋白激酶MDC1和53BP1蛋白之一,目前多用于腫瘤方面的研究。 |
| 產(chǎn)品圖片 |
Western blot analysis of HeLa cell lysate. Using p53BP1 (bsm-61471R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
|
