| 產(chǎn)品編號 | bsm-61497R |
| 英文名稱 | MRP1/ABCC1 Recombinant Rabbit mAb |
| 中文名稱 | 多藥耐藥相關(guān)蛋白1重組兔單抗 |
| 別 名 | ABC29; Abcc1; GSX; Leukotriene C(4) transporter; LTC4 transporter; MRP1. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 172 kDa |
| 檢測分子量 | 171 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ABCC1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Mediates export of organic anions and drugs from the cytoplasm. Mediates ATP-dependent transport of glutathione and glutathione conjugates, leukotriene C4, estradiol-17-beta-o-glucuronide, methotrexate, antiviral drugs and other xenobiotics. Confers resistance to anticancer drugs. Hydrolyzes ATP with low efficiency. SWISS: P33527 Gene ID: 4363 多藥耐藥相關(guān)蛋白1(MRP1)是MRP家族中的一個(gè)成員之一，基因的染色體位點(diǎn)是16p13.1，它編碼分子量是170-190kDa的MRP1蛋白。 MRP1又稱ABCC1主要表達(dá)在消化系統(tǒng)中的肝臟、結(jié)腸和胰腺組織中，常用于多種腫瘤的多藥耐藥機(jī)制的研究。 |
| 產(chǎn)品圖片 |
Western blot analysis of A431 cell lysate. Using MRP1/ABCC1 (bsm-61497R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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