| 產(chǎn)品編號(hào) | bsm-61592R |
| 英文名稱 | PROC Recombinant Rabbit mAb |
| 中文名稱 | 維生素K依賴的蛋白C重組兔單抗 |
| 別 名 | Activation peptide; Anticoagulant protein C; APC; Autoprothrombin IIA; Blood coagulation factor XIV; PROC1; THPH3; THPH4; Vitamin K dependent protein C. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 52 kDa |
| 檢測分子量 | 52 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PROC |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. SWISS: P04070 Gene ID: 5624 活化蛋白C是一種絲氨酸蛋白酶，也是一種抑癌基因，參與細(xì)胞信號(hào)的傳導(dǎo)，在細(xì)胞分裂、細(xì)胞黏附中有重要的作用 有人用于抑制凝血 (抗凝作用)促進(jìn)纖維蛋白溶解及抗炎作用的研究, 近年來有學(xué)者認(rèn)為APC還可以抑制血管內(nèi)皮細(xì)胞凋亡, 有抑制腫瘤壞死因子產(chǎn)生、限制凝血酶誘導(dǎo)炎癥反應(yīng)與微血管內(nèi)皮細(xì)胞的一些作用。 |
| 產(chǎn)品圖片 |
Western blot analysis of HepG2 cell lysate. Using PROC (bsm-61592R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
|
