| 產(chǎn)品編號(hào) | bsm-62076R |
| 英文名稱(chēng) | ODC1 Recombinant Rabbit mAb |
| 中文名稱(chēng) | 鳥(niǎo)氨酸脫羧酶重組兔單抗 |
| 別 名 | Dodc1; ODC; Odc1; ODC2; RNODC. |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Recombinant |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 51 kDa |
| 檢測(cè)分子量 | 51 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Ornithine decarboxylase |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. SWISS: P11926 Gene ID: 4953 鳥(niǎo)氨酸脫羧酶為多胺生物合成途徑中的第一個(gè)限速酶 (催化合成多胺的第一步反應(yīng) ,即催化L -鳥(niǎo)氨酸脫羧生成腐胺 ) ,具有超常轉(zhuǎn)變率和對(duì)于刺激的迅速反應(yīng)性。 多胺廣泛存在于生物體的各種細(xì)胞和組織中 ,是一種重要的代謝調(diào)控物質(zhì) ,它可直接與DNA相互作用 ,調(diào)節(jié)DNA構(gòu)象 ,并參與RNA及蛋白質(zhì)的合成 ,與細(xì)胞增殖、分化密切相關(guān)。經(jīng)研究表明 ,哺乳動(dòng)物細(xì)胞增殖體現(xiàn)出完全的多胺依賴(lài)性。ODC主要存在于胞漿中。 |
| 產(chǎn)品圖片 |
Western blot analysis of K562 cell lysate. Using ODC1 (bsm-62076R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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