| 產(chǎn)品編號(hào) | bsm-62093R |
| 英文名稱 | Phospho-GluR1 (Ser845) Recombinant Rabbit mAb |
| 中文名稱 | 磷酸化谷氨酸受體1重組兔單抗 |
| 別 名 | Glutamate receptor 1; GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; GluRA; GluRK1; Glutamate receptor ionotropic, AMPA 1; GluA1; GRIA1; GLUH1; GLUR1. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 102 kDa |
| 檢測(cè)分子量 | 102 |
| 性 狀 | Liquid |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GluR1 around the phosphorylation site of S845 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
AMPA- (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainate-, and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4), which assemble as homo- or hetero-tetramers to mediate the majority of fast excitatory transmissions in the central nervous system. AMPARs are implicated in synapse formation, stabilization, and plasticity. SWISS: P42261 Gene ID: 2890 NMDAR1又稱GluR1 (Glutamate Receptor 1)近年實(shí)驗(yàn)研究發(fā)現(xiàn)，許多NMDAR拮抗藥均具有鎮(zhèn)痛活性，表明NMDAR在痛覺傳遞中具有重要作用，這為新型鎮(zhèn)痛藥的研究開發(fā)提供了新的作用靶點(diǎn)。 |
| 產(chǎn)品圖片 |
Western blot analysis of (1) Human brain lysate treated with Lambda phosphatase lysate; (2) Human brain lysate. Using Phospho-GluR1 (Ser845) (bsm-62093R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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