| 產(chǎn)品編號 | bs-1685R |
| 英文名稱 | CTNNAL1 Rabbit pAb |
| 中文名稱 | 粘附分子相關(guān)蛋白a1抗體 |
| 別 名 | ACRP; alpha catenin related protein; alpha CATU; alpha catulin; alpha2 catulin; catenin(cadherin associated protein), alpha like 1; Catenin alpha like protein 1; catenin, alpha like 1; CLLP; Highly similar to ALPHA CATENIN; CTNL1_HUMAN; alpha-catulin; alpha-catenin-related protein; Catenin alpha-like protein 1. |
| 研究領(lǐng)域 | 免疫學(xué) 細(xì)胞膜受體 細(xì)胞粘附分子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat (predicted: Human,Mouse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 81 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CTNNAL1: 151-250/743 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
CTNNAL1 acts as a scaffold in the Rho signalling pathway. May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor. There are three different isoforms. Function: May modulate the Rho pathway signaling by providing a scaffold for the Lbc Rho guanine nucleotide exchange factor (ARHGEF1). Subunit: Interacts with ARHGEF1. Subcellular Location: Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Tissue Specificity: Widely expressed. Expressed at lower level in neural tissues and at the highest level in the adrenal gland. Similarity: Belongs to the vinculin/alpha-catenin family. SWISS: Q9UBT7 Gene ID: 8727 Database links: Entrez Gene: 8727 Human Omim: 604785 Human SwissProt: Q9UBT7 Human Unigene: 58488 Human |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (CTNNAL1) Polyclonal Antibody, Unconjugated (bs-1685R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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