| 產(chǎn)品編號(hào) | bs-2639R |
| 英文名稱 | PTGES2 Rabbit pAb |
| 中文名稱 | 前列腺素E合成酶2抗體 |
| 別 名 | C9orf15; FLJ14038; gamma interferon activated transcriptional element binding factor 1; GATE binding factor 1; GBF 1; GBF1; Membrane associated prostaglandin E synthase 2; MGC11289; Microsomal prostaglandin E synthase 2; mPGES 2; mPGES-2; PGES2; PGES2_HUMAN; Prostaglandin E synthase 2; Prostaglandin E synthase 2 truncated form; PTGES 2; PGES2_MOUSE. |
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Specific References (10) | bs-2639R has been referenced in 10 publications.
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| 研究領(lǐng)域 | 腫瘤 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse,Rat (predicted: Pig,Cow,Chicken,Dog) |
| 產(chǎn)品應(yīng)用 | Flow-Cyt=1ug/test
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 43 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from mouse PTGES2: 281-384/384 <Cytoplasmic> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq]. Function: Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form (By similarity). May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear. Subunit: Homodimer. May interact with CEBPB. Subcellular Location: Golgi apparatus membrane; Single-pass membrane protein. Nucleus. Note=According to PubMed:12050152, some fraction may be nuclear. Prostaglandin E synthase 2 truncated form: Cytoplasm. Note=Synthetized as a Golgi membrane-bound protein, which is further cleaved into the predominant soluble truncated form. Tissue Specificity: Widely expressed. Expressed in brain, heart, liver, colon and lung. Similarity: Belongs to the GST superfamily. Contains 1 glutaredoxin domain. Contains 1 GST C-terminal domain. SWISS: Q8BWM0 Gene ID: 96979 Database links: Entrez Gene: 80142 Human Entrez Gene: 96979 Mouse Entrez Gene: 100294563 Sheep Omim: 608152 Human SwissProt: Q9H7Z7 Human SwissProt: Q8BWM0 Mouse Unigene: 495219 Human Unigene: 28048 Mouse |
| 產(chǎn)品圖片 |
Blank control:A549.
Primary Antibody (green line): Rabbit Anti-PTGES2 antibody (bs-2639R)
Dilution: 1μg /10^6 cells;
Isotype Control Antibody (orange line): Rabbit IgG .
Secondary Antibody : Goat anti-rabbit IgG-PE
Dilution: 1μg /test.
Protocol
The
Blank control: HepG2. Primary Antibody (green line): Rabbit Anti-PTGES2 antibody (bs-2639R) Dilution: 2μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody : Goat anti-rabbit IgG-FITC Dilution: 1μg /test. Pr
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