| 產(chǎn)品編號(hào) | bs-2055R |
| 英文名稱 | Integrin alpha 4+Beta 7 Rabbit pAb |
| 中文名稱 | 整合素α4β7抗體 |
| 別 名 | alpha 4 subunit of VLA 4 receptor; Antigen CD49D; CD 49d; CD49d; CD49d antigen; IA 4; IA4; Integrin alpha 4; Integrin alpha 4 subunit; Integrin alpha IV; Integrin beta 7; Integrin beta 7 subunit; ITGA 4; ITGA4; ITGA4 protein; ITGB 7; ITGB7; LPAM 1; LPAM1; MGC90518; Very late activation protein 4 receptor alpha 4 subunit; VLA 4; VLA4. |
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Specific References (2) | bs-2055R has been referenced in 2 publications.
[IF=3.63] Tong, Bei, et al. "Norisoboldine ameliorates collagen-induced arthritis through regulating the balance between Th17 and regulatory T cells in gut-associated lymphoid tissues." Toxicology and Applied Pharmacology (2014). IHC-F ; Rat.
[IF=3] Tong, Bei, et al. "Sinomenine suppresses collagen-induced arthritis by reciprocal modulation of regulatory T cells and Th17 cells in gut-associated lymphoid tissues." Molecular Immunology 65.1 (2015): 94-103. IHC-F ; Rat.
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| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞膜受體 細(xì)胞表面分子 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse,Rat (predicted: Pig,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 114 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Integrin alpha 4+Beta 7 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Integrin alpha 4 beta 7, also known as, the lymphocyte Peyer's patch adhesion molecule (LPAM1) is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. Subcellular Location: Membrane; Single pass type I membrane protein. SWISS: P13612 Gene ID: 3676 Database links: Entrez Gene: 3676 Human Entrez Gene: 16401 Mouse Omim: 192975 Human SwissProt: P13612 Human SwissProt: Q00651 Mouse Unigene: 440955 Human Unigene: 31903 Mouse
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