| 產(chǎn)品編號(hào) | bs-0345P |
| 英文名稱 | Human IgM |
| 中文名稱 | 人IgM |
| 別 名 | human Immunoglobulin M; IgM from human serum; Human IgM Purified; Human IgM Protein (Native). (免疫親和純化)人IgM |
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Specific References (4) | bs-0345P has been referenced in 4 publications.
[IF=4.34] Gao, Hongfei, et al. Amorphous carbon nanoparticle used as novel resonance energy transfer acceptor for chemiluminescent immunoassay of transferrin. Biosensors and Bioelectronics 60 (2014) 224–230. other ;
[IF=2.88] Tang M et al. Quantum dots-based sandwich immunoassay for sensitive detection of Alzheimer's disease-related Aβ1-42.Spectrochim Acta A Mol Biomol Spectrosc. 2018 Aug 5;201:82-87. Other ;
[IF=1.953] Wu et al. Development of a C3c-based ELISA method for the determination of anti-complementary potency of Bupleurum polysaccharides. (2015) Acta.Pharm.Sin.. 5:316-22 ELISA ;
[IF=0] Li L et al. Hypoxia restrains the expression of complement component 9 in tumor-associated macrophages promoting non-small cell lung cancer progression.Cell Death Discov. 2018 Jun 7;4:63. blocking antibodies ;
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| 性 狀 | Lyophilized or Liquid |
| 保存條件 | Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
IgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and is largely confined to plasma due to it's large size. Monomeric IgM is expressed as a membrane bound antibody on the surface of B cells and as a pentamer when secreted by plasma cells. Due to it's high valency IgM is more efficient than other isotypes is binding antigens with repeating epitopes (virus particles and red blood cells) and is more efficient than IgG in activiating the complement pathway. The gene for the mu constant region contains four domains separated by short intervening sequences. |
