| 產(chǎn)品編號 | bs-4299R |
| 英文名稱 | CNTROB Rabbit pAb |
| 中文名稱 | 乳腺癌易感基因2相互作用蛋白抗體 |
| 別 名 | Centrobin; centrobin, centrosomal BRCA2 interacting protein; Centrosomal BRCA2 interacting protein; LIP8; LYST interacting protein 8; CNTRB_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 細(xì)胞周期蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 101 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CNTROB: 51-150/903 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
CNTROB is a centrosomal protein that interacts with BRCA2 and is required for centriole duplication with inhibition of centriole duplication leading to defects in cytokinesis. Function: Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis. Subunit: Interacts with LYST. Subcellular Location: Cytoplasm, cytoskeleton, centrosome, centriole. Note=Centriole-associated, asymmetrically localizes to the daughter centriole. Tissue Specificity: Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes. SWISS: Q8N137 Gene ID: 116840 Database links: Entrez Gene: 116840 Human Omim: 611425 Human SwissProt: Q8N137 Human Unigene: 348012 Human |
