產(chǎn)品編號(hào) | bs-5831R |
英文名稱 | ANKHD1 Rabbit pAb |
中文名稱 | 艾滋病病毒制約錨定蛋白抗體 |
別 名 | ANKH1_HUMAN; ANKHD 1; ANKHD1; Ankyrin repeat and KH domain containing 1; Ankyrin repeat and KH domain containing protein 1; Ankyrin repeat and KH domain-containing protein 1; HIV-1 Vpr-binding ankyrin repeat protein; HIV1 Vpr binding ankyrin repeat protei |
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Specific References (1) | bs-5831R has been referenced in 1 publications.
[IF=6.083] Sun, Wenhuizi. et al. Alternative ANKHD1 transcript promotes proliferation and inhibits migration in uterine corpus endometrial carcinoma. NPJ GENOM MED. 2022 Sep;7(1):1-12 IF ; Human.
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研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 細(xì)菌及病毒 細(xì)胞粘附分子 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Pig,Sheep,Cow,Dog,Horse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 269 kDa |
檢測(cè)分子量 | |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ANKHD1: 1901-2000/2542 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases. Function: May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases. Subunit: Interacts with PTPN11. Isoform 2 interacts with HIV-1 VPR. Subcellular Location: Cytoplasm. Tissue Specificity: Ubiquitous with high expression in cervix, spleen and brain. Expressed in hematopoietic cells with increased expression in leukemia cells. Isoform 2 is highly expressed in spleen with almost no expression in muscle and brain. Similarity: Belongs to the mask family. Contains 25 ANK repeats. Contains 1 KH domain. SWISS: Q8IWZ3 Gene ID: 54882 Database links: Entrez Gene: 54882 Human Omim: 610500 Human SwissProt: Q8IWZ3 Human Unigene: 594084 Human Unigene: 720987 Human |
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