產(chǎn)品編號 | bs-9977R |
英文名稱 | C21orf2 Rabbit pAb |
中文名稱 | 21號染色體開放閱讀框2抗體 |
別 名 | A2 antibody C21orf HUMF09G8.5; Chromosome 21 open reading frame 2; Hypothetical protein LOC755; Nuclear encoded mitochondrial protein cDNA A2 YF5; Uncharacterized protein C21orf2; YF 5; YF5; YF5/A2 antibody. |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 發(fā)育生物學(xué) 神經(jīng)生物學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Rat (predicted: Human,Mouse) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 28 kDa |
檢測分子量 | |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human C21orf2: 1-100/256 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf2 gene product has been provisionally designated C21orf2 pending further characterization. Function: May play roles in cilia formation and/or maintenance (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Similarity: Contains 3 LRR (leucine-rich) repeats. Contains 1 LRRCT domain. To C.elegans F09G8.5. SWISS: O43822 Gene ID: 755 Database links: Entrez Gene: 755 Human Entrez Gene: 67884 Mouse Omim: 603191 Human SwissProt: O43822 Human SwissProt: Q8C6G1 Mouse Unigene: 517331 Human |
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