| 產(chǎn)品編號 | bs-4307R |
| 英文名稱 | Defensin beta 2 Rabbit pAb |
| 中文名稱 | 防御素β2抗體 |
| 別 名 | beta Defensin 2; beta-defensin 2; mBD-2; Defensin, beta 2; Defb2; MGC129140; MGC129141; Skin-antimicrobial peptide 1; SAP1; BD-2; BD 2; BD2; beta 4 Defensin; DEF B2; DEF B4; DEFB 102; DEFB 2; DEFB-2; DEFB 4; DEFB102; DEFB2; DEFB4; Defensin 4 beta; Defensi |
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Specific References (3) | bs-4307R has been referenced in 3 publications.
[IF=4.494] Nur Atalay. et al. Serum, saliva, and gingival tissue human β-defensin levels in relation to retinoic acid use. J PERIODONTOL. 2022 Nov;: IHC ; Human.
[IF=2.38] Al‐Samadi, Ahmed, et al. "Increased beta 2 defensin in recurrent aphthous ulcer." Oral Diseases (2014). IHC-P ; Human.
[IF=0] Shi et al. Overexpression of human β-defensin 2 promotes growth and invasion during esophageal carcinogenesis. (2014) Oncotarget. 5:11333-44 IHC ; Rat.
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| 研究領(lǐng)域 | 細(xì)胞生物 發(fā)育生物學(xué) 細(xì)胞膜蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 4 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human beta 2 Defensin: 24-64/64 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Beta-defensins (also designated BD, and hBD in human) are small cationic peptides with broad-spectrum antimicrobial activity. Produced in mucosal epithelia and neutrophils of several species, Beta-defensins are developmentally regulated. Human b-defensin 2 is locally regulated by inflammation and is the first member of the b-defensin family that is locally inducible by inflammation. The murine homolog of human b-defensin 2, which is called b-defensin 3, is present in the respiratory system and in low levels in the epithelial cells of the intestine and lung. The unique murine b-defensin 2 (Defb2) is not expressed in airways of untreated mice, but is upregulated in the airways by lipopolysaccharide and may contribute to host defense at the mucosal surface of the airways Function: Has antibacterial activity. Subcellular Location: Secreted. Tissue Specificity: Expressed in the skin and respiratory tract. Similarity: Belongs to the beta-defensin family. LAP/TAP subfamily. SWISS: O15263 Gene ID: 1673 Database links: Entrez Gene: 100289462 Human Entrez Gene: 1673 Human Omim: 602215 Human SwissProt: O15263 Human Unigene: 105924 Human Unigene: 721744 Human |
