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GPR88 Rabbit pAb (bs-12017R)  
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產品編號 bs-12017R
英文名稱 GPR88 Rabbit pAb
中文名稱 G蛋白偶聯(lián)受體88抗體
別    名 G protein coupled receptor 88; G protein-coupled receptor 88; G-protein coupled receptor 88; Probable G protein coupled receptor 88; STRG; Striatum specific G protein coupled receptor; GPR88_HUMAN; GPCR88.  
研究領域 細胞生物  神經(jīng)生物學  信號轉導  細胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,Rat (predicted: Human,Rabbit,Cow,Dog)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 38 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human G protein coupled receptor 88: 64-170/384 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR88 (G protein-coupled receptor 88), also known as STRG, is a 384 amino acid multi-pass membrane protein that localizes to the cell membrane and belongs to the G protein coupled receptor family. Expressed exclusively in striatum, GPR88 functions as an orphan receptor that may be involved in signaling pathways throughout the cell. Human GPR88 shares 95% sequence identity with its rat counterpart, suggesting a conserved role between species.

Function:
An orphan receptor belonging to the G-protein coupled receptor 1 family, GPR88 is expressed almost exclusively in striatum.

Subcellular Location:
Cell Membrane; Multi-pass membrane protein

Tissue Specificity:
Expressed almost exclusively in striatum.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q9GZN0

Gene ID:
54112

Database links:

Entrez Gene: 54112 Human

Entrez Gene: 64378 Mouse

Entrez Gene: 64443 Rat

Omim: 607468 Human

SwissProt: Q9GZN0 Human

SwissProt: Q9EPB7 Mouse

SwissProt: Q9ESP4 Rat



產品圖片
Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Rat Cerebrum tissue lysates Primary: Anti-GPR88 (bs-12017R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 38 kDa Observed band size: 47 kDa
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