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FUT11 Rabbit pAb (bs-12259R)  
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產(chǎn)品編號 bs-12259R
英文名稱 FUT11 Rabbit pAb
中文名稱 巖藻糖轉(zhuǎn)移酶11抗體
別    名 FucT-XI; 3)-fucosyltransferase 11; alpha(1, 3) fucosyltransferase 11; alpha-(1; Fuc-TXI; Fucosyltransferase 11(alpha(1, 3) fucosyltransferase); Fucosyltransferase 11; Fucosyltransferase XI; FucT-XI; FUT11; FUT11_HUMAN; Galactoside 3-L-fucosyltransferase 11.  
研究領(lǐng)域 信號轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Rat (predicted: Mouse,Rabbit,Pig,Sheep,Cow,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 56 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human FUT11/FucT-XI: 301-440/492 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Glycosyltransferases that mediate the regio- and stereoselective transfer of sugars, such as the fucosyltransferases, determine cell surface-carbohydrate profiles, which are essential interfaces for biological recognition processes. Fucosyltransferases (FucTs) catalyze the covalent association of fucose to different positional linkages on sugar acceptor molecules. The carbohydrate moieties that are generated are covalently attached to cell surfaces and are necessary to ensure a surface contour that satisfies a variety of physiological roles. FucT-XI is a 492 amino acid single-pass type II membrane protein that belongs to the glycosyltransferase 10 family. Localizing to Golgi apparatus, FucT-XI may act as a fucosyltransferase and exists as two alternatively spliced isoforms. The gene encoding FucT-XI maps to mouse chromosome 14 A3.

Function:
Probable fucosyltransferase.

Subcellular Location:
Golgi apparatus > Golgi stack membrane.

Similarity:
Belongs to the glycosyltransferase 10 family.

SWISS:
Q495W5

Gene ID:
170384

Database links:

Entrez Gene: 170384 Human

SwissProt: Q495W5 Human

Unigene: 588854 Human



產(chǎn)品圖片
Sample: HepG2 Cell (Human) Lysate at 40 ug Primary: Anti-FUT11 (bs-12259R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56 kD
Sample: Hela Cell (Human) Lysate at 40 ug Primary: Anti-FUT11 (bs-12259R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56 kD
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Anti
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