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GGT7 heavy chain Rabbit pAb (bs-13351R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-13351R
英文名稱 GGT7 heavy chain Rabbit pAb
中文名稱 γ-谷氨酰轉(zhuǎn)肽酶7重鏈抗體
別    名 gamma-glutamyltransferase 7 heavy chain; D20S101; dJ18C9.2; gamma glutamyltransferase 4; gamma glutamyltransferase 7; gamma glutamyltransferase like 3; gamma glutamyltransferase like 5; gamma glutamyltranspeptidase 7; gamma glutamyltranspeptidase like 3; GGT 7; GGT4; GGTL3; GGTL5; GGT7_HUMAN.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 52 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Gamma-glutamyltransferase 7 heavy chain: 151-250/662 <Extracellular>
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. [provided by RefSeq, Jul 2008].

Function:
Cleaves glutathione conjugates.

Subunit:
Heterodimer composed of the light and heavy chains. The active site is located in the light chain. Isoform 3 interacts with FAM57A.

Subcellular Location:
Membrane; Single pass type II membrane protein.

Tissue Specificity:
Widely expressed, but at low level, except in the airway epithelial cells. Detected in brain, heart, kidney, liver, lung, spleen, testis and trachea.

Similarity:
Belongs to the gamma-glutamyltransferase family.

Gene ID:
2686

Database links:

 



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