| 產(chǎn)品編號(hào) | bs-10427R |
| 英文名稱 | VAMP1+VAMP2+VAMP3 Rabbit pAb |
| 中文名稱 | 囊泡相關(guān)膜蛋白1,2,3抗體 |
| 別 名 | VAMP-1+2+3; Vesicle Associated Membrane Protein 1; DKFZp686H12131; SYB 1; SYB1; Synaptobrevin 1; Synaptobrevin1; Synaptobrevin-1; VAMP 1; VAMP-1; Vesicle associated membrane protein 1; Vesicle associated membrane protein 1 synaptobrevin 1; VAMP1_HUMAN; Ve |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 神經(jīng)生物學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse,Rat (predicted: Rabbit,Pig,Cow,Chicken,Dog,GuineaPig,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 13/11 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human VAMP-1+2+3: 21-118/118 <Cytoplasmic> |
| 亞 型 | |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation. [provided by RefSeq, Jul 2008]. Function: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network. Subunit: Interacts with VAPA and VAPB. Subcellular Location: Membrane; Single-pass type IV membrane protein (Probable). Cell junction, synapse, synaptosome. Tissue Specificity: Nervous system, skeletal muscle and adipose tissue. Similarity: Belongs to the synaptobrevin family. Contains 1 v-SNARE coiled-coil homology domain. SWISS: P23763 Gene ID: 6843 Database links: Entrez Gene: 6843 Human Entrez Gene: 6844 Human Entrez Gene: 9341 Human Entrez Gene: 22317 Mouse Entrez Gene: 22318 Mouse Entrez Gene: 22319 Mouse Omim: 185880 Human Omim: 185881 Human Omim: 603657 Human SwissProt: P23763 Human SwissProt: P63027 Human SwissProt: Q15836 Human SwissProt: P63024 Mouse SwissProt: P63044 Mouse SwissProt: Q62442 Mouse Unigene: 20021 Human Unigene: 25348 Human Unigene: 66708 Human Unigene: 273930 Mouse Unigene: 28643 Mouse Unigene: 32321 Mouse Unigene: 12939 Rat Unigene: 219999 Rat Unigene: 31977 Rat |
