| 產(chǎn)品編號 | bs-13832R |
| 英文名稱 | CEMP1 Rabbit pAb |
| 中文名稱 | 牙骨質(zhì)蛋白1抗體 |
| 別 名 | Cementoblastoma-derived protein 1; Cementum protein 1; Cementum protein 23; CEMP1; CEMP1_HUMAN; CP-23; CP23. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 26 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CEMP1: 151-247/247 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
A mineralized connective tissue known as cementum covers the root surfaces of teeth and is required for maturation of periodontal tissue. CEMP1 (cementum protein 1), also designated CP23 or cementoblastoma-derived protein 1, is a 247 amino acid nuclear and cytoplasmic protein that is thought to regulate cementoblast behavior. Expressed specifically in periodontal ligament and cementum, CEMP1 may play a role in differentiation and mineralization of non-osteogenic cells. The gene encoding CEMP1 maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6. Subcellular Location: Cytoplasm. Tissue Specificity: Detected in periodontal ligament, cementum, cementoblasts and cementoblastoma. SWISS: Q6PRD7 Gene ID: 752014 Database links: Entrez Gene: 752014 Human Omim: 611113 Human SwissProt: Q6PRD7 Human Unigene: 433499 Human Unigene: 737156 Human Unigene: 743305 Human |
