| 產(chǎn)品編號 | bs-13889R |
| 英文名稱 | CHCHD7 Rabbit pAb |
| 中文名稱 | 卷曲螺旋結(jié)構(gòu)域蛋白CHCHD7抗體 |
| 別 名 | Coiled coil helix coiled coil helix domain containing 7; Coiled coil helix coiled coil helix domain containing protein 7; COX23; CHCH7_HUMAN; COX23 cytochrome c oxidase assembly homolog. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 10 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CHCHD7: 41-85/85 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
CHCHD7 is an 85 amino acid protein that contains one CHCH domain. A chromosomal translocation involving the CHCHD7 gene and PLAG1 gene is found in salivary gland pleiomorphic adenomas, the most common benign epithelial tumors of the salivary gland. There are three isoforms of CHCHD7 that are produced as a result of alternative splicing events. The gene encoding CHCHD7 maps to human chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. Subunit: Monomer. Subcellular Location: Mitochondrion intermembrane space DISEASE: Note=A chromosomal aberration involving CHCHD7 is found in salivary gland pleiomorphic adenomas, the most common benign epithelial tumors of the salivary gland. Translocation t(6;8)(p21.3-22;q13) with PLAG1. Similarity: Belongs to the CHCHD7 family. Contains 1 CHCH domain. SWISS: Q9BUK0 Gene ID: 79145 Database links: Entrez Gene: 79145 Human Omim: 611238 Human SwissProt: Q9BUK0 Human Unigene: 436913 Human |
