產(chǎn)品編號 | bs-16779R |
英文名稱 | Rabbit Anti-Klra3 antibody |
中文名稱 | 自然殺傷細(xì)胞凝集素樣受體3(Ly 49c)抗體 |
別 名 | KLRA3_MOUSE; 5E6; Killer cell lectin like receptor 3; Killer cell lectin like receptor subfamily A member 3; KLRA 3; Ly 49c; Ly49C; Lymphocyte antigen 49c; MGC123910; Natural killer cell associated antigen 2; Nk 2; NK 2.1; Nk2; Nk2.1; OTTMUSP00000026267; T cell surface glycoprotein Ly 49C. KLRA3/Ly49C |
研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 細(xì)胞膜受體 自然殺傷細(xì)胞 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 31 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from mouse KLRA3: 51-150/266 <Extracellular> |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
KLRA3 (also known as Ly49C) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA3 is thought to be an inhibitory receptor, recognizing peptide–receptive H-2Kb. Function: Receptor on natural killer (NK) cells for class I MHC. Subcellular Location: Membrane; Single-pass type II membrane protein. Similarity: Contains 1 C-type lectin domain. SWISS: Q64329 Gene ID: 16634 Database links: Entrez Gene: 16634 Mouse SwissProt: Q64329 Mouse |
產(chǎn)品圖片 | |
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