| 產(chǎn)品編號(hào) | bs-16812R |
| 英文名稱 | KREMEN1 Rabbit pAb |
| 中文名稱 | KREMEN1蛋白抗體 |
| 別 名 | AV002070; Dickkopf receptor; KREM1_HUMAN; KREMEN; Kremen protein 1; Kremen protein 1 precursor; Kremen1; Kringle coding gene marking the eye and the nose; Kringle containing protein marking the eye and the nose; Kringle containing transmembrane protein 1; |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞膜受體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Sheep,Cow) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 50 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KREMEN1: 101-200/473 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008] Function: Receptor for Dickkopf protein. Cooperates with Dickkopf to block Wnt/beta-catenin signaling (By similarity). {ECO:0000250}. Subcellular Location: Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Similarity: Contains 1 CUB domain. SWISS: Q96MU8 Gene ID: 83999 Database links: Entrez Gene: 83999 Human Omim: 609898 Human SwissProt: Q96MU8 Human Unigene: 229335 Human |
| 產(chǎn)品圖片 |
Sample: Heart (Mouse) Lysate at 40 ug
Primary: Anti-KREMEN1 (bs-16812R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 50 kD
Observed band size: 50 kD
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