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KCTD1 Rabbit pAb (bs-16924R)  
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產(chǎn)品編號(hào) bs-16924R
英文名稱(chēng) KCTD1 Rabbit pAb
中文名稱(chēng) 鉀離子通道多聚體結(jié)構(gòu)域蛋白1抗體
別    名 BTB/POZ domain-containing protein KCTD1; C18orf5; Kctd1; KCTD1_HUMAN; Potassium channel tetramerisation domain containing 1; Potassium channel tetramerization domain-containing protein 1.  
研究領(lǐng)域 細(xì)胞生物  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 29 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human KCTD1: 201-257/257 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 KCTD1 (potassium channel tetramerisation domain containing 1), also known as C18orf5, is a 257 amino acid protein that contains one BTB domain, suggesting an involvement in transcriptional control. The gene encoding KCTD1 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.

Function:
May repress the transcriptional activity of AP-2 family members, including TFAP2A, TFAP2B and TFAP2C to various extent.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in mammary gland, kidney, brain and ovary.

Post-translational modifications:
Sumoylated.

Similarity:
Contains 1 BTB (POZ) domain.

SWISS:
Q719H9

Gene ID:
284252

Database links:

Entrez Gene: 284252 Human

Omim: 613420 Human

SwissProt: Q719H9 Human

Unigene: 526630 Human



產(chǎn)品圖片
Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Mouse Kidney tissue lysates Primary: Anti-KCTD1 (bs-16924R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 29 kDa Observed band size: 33 kDa
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