| 產(chǎn)品編號 | bs-18162R |
| 英文名稱 | TNS4 Rabbit pAb |
| 中文名稱 | 張力蛋白4抗體 |
| 別 名 | C terminal tensin like; C terminal tensin like protein; C-terminal tensin-like protein; CTEN; c-TEN; FLJ14950; PP14434; TENS4_HUMAN; Tensin 4; Tensin-4. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 細(xì)胞粘附分子 細(xì)胞骨架 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 75 kDa |
| 檢測分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TNS4: 401-500/715 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Predicted to enable actin binding activity. Involved in protein localization. Located in focal adhesion. [provided by Alliance of Genome Resources, Nov 2021] Function: May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity). May promote apoptosis, via its cleavage by caspase-3. Subcellular Location: Cell junction > focal adhesion. Cytoplasm > cytoskeleton. Tissue Specificity: Prostate and placenta. Down regulated in prostate cancer. Post-translational modifications: Proteolytically cleaved by caspase-3 during apoptosis. Similarity: Contains 1 phosphatase tensin-type domain. Contains 1 SH2 domain. SWISS: Q8IZW8 Gene ID: 84951 Database links: Entrez Gene: 84951 Human Entrez Gene: 217169 Mouse Omim: 608385 Human SwissProt: Q8IZW8 Human SwissProt: Q8BZ33 Mouse Unigene: 438292 Human Unigene: 262067 Mouse |
