產(chǎn)品編號 | bs-18191R |
英文名稱 | LCMT2 Rabbit pAb |
中文名稱 | LCMT2蛋白抗體 |
別 名 | KIAA0547; LCMT 2; Lcmt2; LCMT2_HUMAN; Leucine carboxyl methyltransferase 2; MGC9534; p21WAF1/CIP1 promoter interacting protein; p21WAF1/CIP1 promoter-interacting protein; PPM2; tRNA Wybutosine synthesizing protein 4; tRNA wybutosine synthesizing protein 4 |
研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human,Mouse,Rat,Cow) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 76 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human LCMT2: 321-420/686 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW). [provided by RefSeq, Jul 2008] Function: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues. Similarity: Belongs to the methyltransferase superfamily. LCMT family. SWISS: O60294 Gene ID: 9836 Database links: Entrez Gene: 9836 Human Omim: 611246 Human SwissProt: O60294 Human Unigene: 200596 Human Unigene: 533913 Human Unigene: 741946 Human Unigene: 17983 Rat |
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