| 產(chǎn)品編號(hào) | bs-10693R |
| 英文名稱 | KIF15 Rabbit pAb |
| 中文名稱 | 驅(qū)動(dòng)蛋白家族成員15抗體 |
| 別 名 | Kinesin like protein 7; KLP2; FLJ25667; HKLP2; Kinesin family member 15; Kinesin like protein 2; Kinesin like protein 7; Kinesin like protein KIF15; KLP2; KNSL7; Linesin like 7; NY BR 62; NYBR62; Serologically defined breast cancer antigen NY BR 62; Serol |
| 研究領(lǐng)域 | 細(xì)胞生物 細(xì)胞骨架 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 160 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KIF15: 101-200/1388 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
KIF15 belongs to the kinesin-like protein family and contains 1 kinesin-motor domain. KIF15 is the plus-end directed kinesin-like motor enzyme involved in mitotic spindle assembly. Function: Plus-end directed kinesin-like motor enzyme involved inmitotic spindle assembly. Subunit: Interacts with MKI67 and TPX2. Subcellular Location: Cytoplasm. Cytoplasm, cytoskeleton, spindle.Note=Detected during the interphase in the cytoplasm as finelypunctuate pattern and irregularly shaped dots. Detected duringmitosis on the mitotic spindle. Colocalizes with TPX2 in mitosis.Localizes at the central spindle at anaphase.Localizes at the sites of invaginating cell membranes, a positionthat corresponds to the location of the contractile actomyosin ringof dividing cells. Colocalizes with actin ininterphase. Colocalizes in dendrites and in growthcone of axons with microtubules. Tissue Specificity: Highly expressed in liver and weakly in testis. Expression was higher in patients with severe fibrosis or inflammation and chronic hepatitis. Similarity: Belongs to the kinesin-like protein family. KLP2subfamily. Contains 1 kinesin-motor domain. SWISS: Q9NS87 Gene ID: 56992 Database links: Entrez Gene: 56992 Human Entrez Gene: 209737 Mouse SwissProt: Q9NS87 Human SwissProt: Q6P9L6 Mouse
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