產(chǎn)品編號 | bs-18792R |
英文名稱 | MED12L Rabbit pAb |
中文名稱 | 甲狀腺激素受體相關(guān)蛋白復(fù)合物230樣蛋白抗體 |
別 名 | MD12L_HUMAN; MED12L; Mediator complex subunit 12-like protein; Mediator of RNA polymerase II transcription subunit 12-like protein; NOPAR; Thyroid hormone receptor-associated-like protein; TNRC11L; TRALP; TRALPUSH; Trinucleotide repeat-containing gene 11 protein-like. |
研究領(lǐng)域 | 細(xì)胞生物 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 240 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MED12L: 601-700/2145 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery. [provided by RefSeq, May 2010] Function: May be a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Subunit: Belongs to the Mediator complex subunit 12 family. Subcellular Location: Nucleus. Similarity: Belongs to the Mediator complex subunit 12 family. SWISS: Q86YW9 Gene ID: 116931 Database links: Entrez Gene: 116931 Human Omim: 611318 Human SwissProt: Q86YW9 Human Unigene: 58561 Human Unigene: 730822 Human |
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