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RQCD1 Rabbit pAb (bs-18842R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產品編號 bs-18842R
英文名稱 RQCD1 Rabbit pAb
中文名稱 細胞分化蛋白質RCD1抗體
別    名 CAF40; CCR4-NOT transcription complex subunit 9; Cell differentiation protein RCD1 homolog; CNOT9; CT129; Homo sapiens protein involved in sexual development complete cds; Rcd 1; Rcd-1; Rcd1(required for cell differentiation, S.pombe) homolog 1; RCD1; RCD1 required for cell differentiation1 homolog; RCD1 required for cell differentiation1 homolog(S. pombe); RCD1+; RCD1_HUMAN; rqcd1.  
研究領域 細胞生物  轉錄調節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Zebrafish,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 33 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RQCD1: 81-180/299 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a member of the highly conserved RCD1 protein family. The encoded protein is a transcriptional cofactor and a core protein of the CCR4-NOT complex. It may be involved in signal transduction as well as retinoic acid-regulated cell differentiation and development. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2012]

Function:
Transcription factor that down-regulates MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A.

Subcellular Location:
Nucleus. Cytoplasm > P-body. NANOS2 promotes its localization to P-body.

Tissue Specificity:
Detected in spleen, thymus, prostate, testis, ovary and intestine.

Similarity:
Belongs to the RCD1 family.

SWISS:
Q92600

Gene ID:
9125

Database links:

Entrez Gene: 9125 Human

Omim: 612054 Human

SwissProt: Q92600 Human

Unigene: 148767 Human



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