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FABP6 Rabbit pAb (bs-10931R)  
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50ul/1180.00元
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產(chǎn)品編號 bs-10931R
英文名稱 FABP6 Rabbit pAb
中文名稱 回腸脂肪酸結(jié)合蛋白抗體
別    名 Fatty acid binding protein 6, ileal(gastrotropin); Gastrotropin; GT antibody I 15P; I BABP; I BALB; I BAP; I15P; IBABP; IBALB; IBAPv ILBP; ILBP3; Ileal lipid binding protein; ILLBP; Intestinal 15 kDa protein; Intestinal bile acid binding protein; FABP6_HU  
Specific References  (1)     |     bs-10931R has been referenced in 1 publications.
[IF=1.966] Zhang Y et al. High expression of FABP4 and FABP6 in patients with colorectal cancer. World J Surg Oncol. 2019 Oct 24;17(1):171.  IHC-P&WB ;  Human.  
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Horse)
產(chǎn)品應(yīng)用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 14 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FABP6: 61-128/128 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.

Subcellular Location:
Cytoplasm and Cytoplasm. Localized close to nucleus on the apical side of both normal and neoplastic cells

Tissue Specificity:
Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is expressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum.

Similarity:
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

SWISS:
P51161

Gene ID:
2172

Database links:

Entrez Gene: 2172 Human

Entrez Gene: 16204 Mouse

Entrez Gene: 25440 Rat

Omim: 600422 Human

SwissProt: P51161 Human

SwissProt: P51162 Mouse

SwissProt: P80020 Rat

Unigene: 519719 Human

Unigene: 142716 Mouse

Unigene: 10008 Rat



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