| 產(chǎn)品編號(hào) | bs-19833R |
| 英文名稱(chēng) | SLC39A5 Rabbit pAb |
| 中文名稱(chēng) | 溶質(zhì)載體家族蛋白39成員A5抗體 |
| 別 名 | LZT Hs7; MGC34778; OTTHUMP00000211153; OTTHUMP00000211154; S39A5_HUMAN; SLC39A5; solute carrier family 39(metal ion transporter), member 5; Solute carrier family 39 member 5; Zinc transporter ZIP5 [Precursor]; Zinc transporter ZIP5; ZIP 5; ZIP-5; ZIP5; Zr |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Cow,Dog,Cat,GuineaPig,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 57 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SLC39A5: 21-100/540 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
The protein encoded by this gene belongs to the ZIP family of zinc transporters that transport zinc into cells from outside, and play a crucial role in controlling intracellular zinc levels. Zinc is an essential cofactor for many enzymes and proteins involved in gene transcription, growth, development and differentiation. Mutations in this gene have been associated with autosomal dominant high myopia (MYP24). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014] Function: May play a role in polarized cells by carrying out serosal-to-mucosal zinc transport. Seems to play a central role in controlling organismal zinc status. Subcellular Location: Basolateral cell membrane. Tissue Specificity: Expressed in liver, kidney, pancreas, small intestine, colon, spleen, fetal liver and fetal kidney. Post-translational modifications: Glycosylated. Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. SWISS: Q6ZMH5 Gene ID: 283375 Database links: Entrez Gene: 283375 Human Entrez Gene: 72002 Mouse GenBank: NM_173596 Human Omim: 608730 Human SwissProt: Q6ZMH5 Human SwissProt: Q9D856 Mouse Unigene: 591018 Human Unigene: 22983 Mouse |
