產(chǎn)品編號 | bs-21038R |
英文名稱 | ROD1/PTBP3 Rabbit pAb |
中文名稱 | 調(diào)節(jié)分化蛋白ROD1抗體 |
別 名 | DKFZp781I1117; Fission yeast differentiation regulator; OTTHUMP00000021931; OTTHUMP00000021932; Polypyrimidine tract binding protein 3; regulator of differentiation 1; Regulator of differentiation(in S. pombe) 1; Regulator of differentiation 1; ROD 1; Rod1; ROD1 regulator of differentiation 1; ROD1_HUMAN. |
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Specific References (1) | bs-21038R has been referenced in 1 publications.
[IF=2.095] Zhou W et al. MiR-384 inhibits proliferation and migration of trophoblast cells via targeting PTBP3. Pregnancy Hypertens
. 2020 Jul;21:132-138. WB ; Human.
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研究領(lǐng)域 | 細(xì)胞生物 結(jié)合蛋白 細(xì)胞分化 表觀遺傳學(xué) |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse,Rat (predicted: Human,Rabbit,Pig,Sheep,Cow,Zebrafish,Dog,Horse,Danio) |
產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 60 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ROD1/PTBP3: 201-300/552 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] Function: RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U). Subcellular Location: Contains 4 RRM (RNA recognition motif) domains. Tissue Specificity: Expressed in several hematopoietic cell lines examined. Similarity: Contains 4 RRM (RNA recognition motif) domains. SWISS: O95758 Gene ID: 9991 Database links: Entrez Gene: 9991 Human Entrez Gene: 230257 Mouse Omim: 607527 Human SwissProt: O95758 Human SwissProt: Q8BHD7 Mouse Unigene: 269988 Human Unigene: 331640 Mouse Unigene: 162818 Rat |
產(chǎn)品圖片 | |
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