| 產(chǎn)品編號(hào) | bs-12780R |
| 英文名稱 | VRK2 Rabbit pAb |
| 中文名稱 | 絲氨酸/蘇氨酸蛋白激酶vrk2抗體 |
| 別 名 | 2810003O05Rik; AI447698; EC 2.7.11.1; Serine/threonine protein kinase VRK2; Serine/threonine-protein kinase VRK2; Vaccinia related kinase 2; Vaccinia virus B1R related kinase 2; Vaccinia-related kinase 2; VRK 2; VRK2; VRK2_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse (predicted: Human,Rat,Chicken) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 58 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human VRK2: 151-250/508 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014] Function: Probable serine/threonine kinase. Subcellular Location: Membrane. Tissue Specificity: Widely expressed. Highly expressed in fetal liver, skeletal muscle, pancreas, heart, peripheral blood leukocytes and testis. Similarity: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. VRK subfamily. Contains 1 protein kinase domain. SWISS: Q86Y07 Gene ID: 7444 Database links: Entrez Gene: 7444 Human Entrez Gene: 69922 Mouse Omim: 602169 Human SwissProt: Q86Y07 Human SwissProt: Q8BN21 Mouse Unigene: 728198 Human Unigene: 285351 Mouse |
| 產(chǎn)品圖片 |
Sample:
Embryo (Mouse) Lysate at 40 ug
Liver (Mouse) Lysate at 40 ug
Primary: Anti-VRK2 (bs-12780R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 58 kD
Observed band size: 58 kD
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