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RASSF10 Rabbit pAb (bs-21165R)  
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產(chǎn)品編號 bs-21165R
英文名稱 RASSF10 Rabbit pAb
中文名稱 RASSF10蛋白抗體
別    名 4632411J06Rik; Ras association(RalGDS/AF 6) domain family(N terminal) member 10; Ras association(RalGDS/AF-6) domain family(N-terminal) member 10; ras association domain containing protein 10; Ras association domain-containing protein 10; RASFA_HUMAN; RASSF10.  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse (predicted: Human,Rat,Rabbit,Pig,Cow,Chicken,Dog)
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 57 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RASSF10: 51-150/507 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 RASSF10 (Ras Association Domain Family Member 10) is a Protein Coding gene. An important paralog of this gene is RASSF9.

Tissue Specificity:
Expressed in brain. Tends to be down-regulated in astrocytic gliomas due to promoter methylation. Methylation occurs early in gliomagenesis and the extent of methylation parallels with higher glioma grades, so that methylation is observed in close to 70% WHO grade IV primary glioblastomas, but not in grade I astrocytomas.

DISEASE:
During interphase, predominantly cytoplasmic, although some nuclear staining in several tumor cell contexts. During prophase, observed at developing centrosomes. Displays persistent localization with centrosomally radiating microtubule bundles until late telophase. Associates with spindle poles particularly during metaphase and anaphase before relocating back to the cytoplasm.

Similarity:
Contains 1 Ras-associating domain.

SWISS:
A6NK89

Gene ID:
644943

Database links:

Entrez Gene: 644943 Human

SwissProt: A6NK89 Human

Unigene: 134650 Human



產(chǎn)品圖片
Sample: Testis (Mouse) Lysate at 40 ug Primary: Anti-RASSF10 (bs-21165R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kD Observed band size: 57 kD
Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-RASSF10 (bs-21165R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kD Observed band size: 57 kD
Sample: Lung (Mouse) Lysate at 40 ug Primary: Anti-RASSF10 (bs-21165R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kD Observed band size: 57 kD
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