產(chǎn)品編號 | bs-23546R |
英文名稱 | MTCH1 Rabbit pAb |
中文名稱 | 線粒體載體同源物1抗體 |
別 名 | Cell proliferation inducing protein 60; CGI-64; CGI64; Mitochondrial carrier homolog 1; Mitocondrial Carrier Homolog 1; MTCH 1; MTCH1_HUMAN; Presenilin Associated Protein; Presenilin-associated protein; PSAP. |
研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) 信號轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 線粒體 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse (predicted: Human,Rat,Pig,GuineaPig) |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 42 kDa |
檢測分子量 | |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 線粒體 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human MTCH1: 1-100/389 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012] Function: Potential mitochondrial transporter. May play a role in apoptosis. Subunit: Interacts with PSEN1. Subcellular Location: Mitochondrion inner membrane; Multi-pass membrane protein (Potential). Tissue Specificity: Widely expressed with a predominant expression in brain. Similarity: Belongs to the mitochondrial carrier family. Contains 2 Solcar repeats. SWISS: Q9NZJ7 Gene ID: 23787 Database links: Entrez Gene: 23787 Human Omim: 610449 Human SwissProt: Q9NZJ7 Human Unigene: 485262 Human |
產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (MTCH1) Polyclonal Antibody, Unconjugated (bs-23546R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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