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PLTP Rabbit pAb (bs-21706R)  
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產(chǎn)品編號 bs-21706R
英文名稱 PLTP Rabbit pAb
中文名稱 磷脂轉(zhuǎn)移蛋白抗體
別    名 HDLCQ9; High density lipoprotein cholesterol level quantitative trait locus 9, included; Lipid transfer protein II; OD107; phospholipid transfer protein; Plasma phospholipid transfer protein; PLTP_HUMAN.  
研究領域 腫瘤  細胞生物  免疫學  轉(zhuǎn)錄調(diào)節(jié)因子  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Rat,Rabbit)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 53 kDa
檢測分子量
細胞定位 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PLTP: 170-270/493 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is one of at least two lipid transfer proteins found in human plasma. The encoded protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism. At least two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Function:
Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein remnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion. Two distinct forms of PLTP exist in plasma: an active form that can transfer PC from phospholipid vesicles to high-density lipoproteins (HDL), and an inactive form that lacks this capability.

Subcellular Location:
Secreted.

Tissue Specificity:
Wide tissue distribution. Placenta > pancreas > lung > kidney > heart > liver > skeletal muscle > brain.

Similarity:
Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

SWISS:
P55058

Gene ID:
5360

Database links:

Entrez Gene: 5360 Human

Entrez Gene: 18830 Mouse

Entrez Gene: 296371 Rat

Omim: 172425 Human

SwissProt: P55058 Human

SwissProt: P55065 Mouse

Unigene: 439312 Human

Unigene: 6105 Mouse

Unigene: 117434 Rat



產(chǎn)品圖片
Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti- PLTP (bs-21706R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 53 kD Observed band size: 53 kD
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