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SSTR4 Rabbit pAb (bs-21861R)  
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產(chǎn)品編號 bs-21861R
英文名稱 SSTR4 Rabbit pAb
中文名稱 生長抑素受體4抗體
別    名 somatostatin receptor 4; Smstr4; Somatostatin receptor type 4; SS 4R; SS4R; SST R4; SSTR 4; SSTR4; SSR4_HUMAN.  
研究領(lǐng)域 腫瘤  細胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Pig,Chicken)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 42 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SSTR4 : 101-200/388 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR4 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in fetal and adult brain and lung. Its function is to inhibit the release of many hormones and other secretory proteins.

Function:
Receptor for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. It is functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
P31391

Gene ID:
6754

Database links:
Entrez Gene: 6754 Human

Entrez Gene: 20608 Mouse

Entrez Gene: 25555 Rat

Omim: 182454 Human

SwissProt: P31391 Human

SwissProt: P49660 Mouse

SwissProt: P30937 Rat

Unigene: 673846 Human

Unigene: 35324 Mouse

Unigene: 9936 Rat



產(chǎn)品圖片
Sample: Stomach (Mouse) Lysate at 40 ug Primary: Anti- SSTR4 (bs-21861R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD
Sample: Cerebrum (Mouse) Lysate at 40 ug Primary: Anti-SSTR4 (bs-21861R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD
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