| 產(chǎn)品編號(hào) | D58000 |
| 英文名稱(chēng) | Sunvozertinib |
| 中文名稱(chēng) | 舒沃替尼 |
| 別 名 | DZD9008; DZD 9008; DZD-9008 |
| CAS | 2370013-12-8 |
| 理論分子量 | 584.09 kDa |
| 檢測(cè)分子量 | |
| 保存條件 | Powder: -20℃ for 3 years | In solvent: -80℃ for 1 year |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
Sunvozertinib is a potent ErbBs and BTK inhibitor and has inhibitory effects on EGFR, Her2 and mutant epidermal growth factor. Sunvozertinib showed inhibition of EGFR exon 20 NPH insertion, EGFR exon 20 ASV insertion, EGFR L858R and T790M mutation, and Her2 exon 20 YVMA and EGFR WT A431. IC50 were 20.4, 20.4, 1.1, 7.5 and 80.4 nM, respectively. |
