產(chǎn)品編號(hào) | D60059 |
英文名稱 | Autophinib |
中文名稱 | |
克 隆 號(hào) | |
CAS | 1644443-47-9 |
理論分子量 | 346.72854 kDa |
檢測(cè)分子量 | |
保存條件 | -20℃ |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Autophinib is a potent, selective autophagy inhibitor with IC50s of 90 nM and 40 nM for starvation- and Rapamycin-induced autophagy, respectively. Autophinib is also an ATP competitive Vacuolar Protein Sorting 34 (VPS34) inhibitor with an IC50 of 19 nM. Autophinib inhibits autophagy induced by starvation or Rapamycin by targeting VPS34 |