產(chǎn)品編號(hào) | bsm-63224R |
英文名稱(chēng) | phospho-MLKL (S358) Recombinant Rabbit mAb |
中文名稱(chēng) | 磷酸化MLKL重組兔單抗 |
別 名 | hMLKL; Mlkl. |
抗體來(lái)源 | Rabbit |
克隆類(lèi)型 | Recombinant |
克 隆 號(hào) | 5B5 |
交叉反應(yīng) | Human |
產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:50-200,IHC-F=1:50-200,IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 54 kDa |
檢測(cè)分子量 | 54 |
性 狀 | Liquid |
免 疫 原 | KLH conjugated synthetic peptide derived from human MLKL around the phosphorylation site of S358 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process.Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. SWISS: Q8NB16 Gene ID: 197259 |