產(chǎn)品編號(hào) | IHC0348H |
英文名稱 | Human K63-linkage specific ubiquitin Ready-To-Use IHC Kit |
中文名稱 | 人泛素蛋白(K63-linkage)即用型免疫組化試劑盒 |
別 名 | 0610006J14Rik, 1810034D23Rik, 2700054O04Rik, AI194771, AL033289, CEP52, CEP80, D8Ertd21e, Gm1863, HEL-S-50, HEL112, HMG20, HUBCEP52, L40, polyubiquitin-C, RPL40, RPS27A, rps27a.L, RPS27L, S27A, TI-225, UBA52, UBA80, UBB, Ubb2, UBC, UBCEP1, UBCEP2, UBCEP80 |
適用樣品基質(zhì) | FFPE tissue |
保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
產(chǎn)品介紹 |
Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi. Multiple alternatively spliced transcript variants that encode the same proteins have been identified. SWISS: P0CG47 Gene ID: 7314 |
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