| 產(chǎn)品編號(hào) | IHC0500M |
| 英文名稱 | Mouse SDHB Ready-To-Use IHC Kit |
| 中文名稱 | 小鼠鉻細(xì)胞瘤患者抑癌基因SDHB即用型免疫組化試劑盒 |
| 別 名 | 0710008N11Rik; CWS2; IP; PGL4; SDH; SDH1; SDH2; SDHB; SDHIP; succinate dehydrogenase complex iron sulfur subunit B |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis. SWISS: P21912 Gene ID: 6390 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded mouse heart tissue slide using IHC0500M (Mouse SDHB IHC Kit).
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