强伦轩一级A片在线观看,中文字幕乱码人妻二区三区,鲁鲁狠狠狠7777一区二区,西西4444www无码精品
掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
免费黃色三級片在线观看18,国产精品成人一区二区无码久久
Rabbit Anti-GLP-1/Biotin Conjugated antibody (bs-0933R-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-0933R-Bio
英文名稱 Rabbit Anti-GLP-1/Biotin Conjugated antibody
中文名稱 生物素標(biāo)記的胰高血糖素樣肽-1抗體
別    名 GCG; GLP 1; glucagon; Glucagon like peptide 1; GRPP; GLP-1(7-36); GLP-1(7-37); Oxyntomodulin; OXM; OXY; GLUC_HUMAN  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  心血管  免疫學(xué)  神經(jīng)生物學(xué)  信號轉(zhuǎn)導(dǎo)  通道蛋白  糖尿病  內(nèi)分泌病  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 21kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated GLP-1 peptide
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq].

Function:
Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes.
GLP-1 is a potent stimulator of glucose-dependent insulin release. Play important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Have growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation. Inhibits beta cell apoptosis.
GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability.
Oxyntomodulin significantly reduces food intake. Inhibits gastric emptying in humans. Suppression of gastric emptying may lead to increased gastric distension, which may contribute to satiety by causing a sensation of fullness.
Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life.

Subunit:
Secreted.

Tissue Specificity:
Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain.

Post-translational modifications:
Proglucagon is post-translationally processed in a tissue-specific manner in pancreatic A cells and intestinal L cells. In pancreatic A cells, the major bioactive hormone is glucagon cleaved by PCSK2/PC2. In the intestinal L cells PCSK1/PC1 liberates GLP-1, GLP-2, glicentin and oxyntomodulin. GLP-1 is further N-terminally truncated by post-translational processing in the intestinal L cells resulting in GLP-1(7-37) GLP-1-(7-36)amide. The C-terminal amidation is neither important for the metabolism of GLP-1 nor for its effects on the endocrine pancreas.

Similarity:
Belongs to the glucagon family.

Database links:

Entrez Gene: 2641 Human

Entrez Gene: 14526 Mouse

Entrez Gene: 24952 Rat

Omim: 138030 Human

SwissProt: P01275 Human

SwissProt: P55095 Mouse

SwissProt: P06883 Rat

Unigene: 516494 Human

Unigene: 45494 Mouse

Unigene: 54383 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

胰高血糖素(Glucagon)在糖代謝和體內(nèi)平衡中起重要作用,通過釋放糖原和糖酵解調(diào)節(jié)血糖。作為反調(diào)節(jié)激素的胰島素,當(dāng)血糖升高時,胰島素可誘導(dǎo)低血糖。
胰高血糖素樣肽-1(Glucagon-like peptide-1, GLP-1)是一個具有強(qiáng)的刺激糖依賴的胰島素釋放的肽,在胃運(yùn)動性和抑制血糖水平上起重要作用。還可能參與外周組織糖的控制,不依賴胰島素的作用。具有促進(jìn)腸上皮生長等作用。GLP-1屬于胰高血糖素家族成員。
版權(quán)所有 2004-2026 www.nmgps.com 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
女生可以看的黄色视频 | 91丝袜精品久久久久久无码人妻 | 污网站免费观看永久免费 | 国产成人精品AA毛片 | 久久久久91精品視頻亞洲一區二區三區 | 亚洲成人无码av | 国产伦子伦一级A片在线 | 韩国一区二区三区在线视频播放 | 日本三级片免费看 | 最好看2018年的中文字幕电影 | 日本无码熟人中文字幕 | 国产初高中小泬视频 | 国产一区二区三区中文字幕 | 国产太孟太爽太大太长视频 | 无套内谢少妇无套内谢视频 | 色情午夜 码一区二区 | 女人被添全过程A片添 | 国产一级黄片aaa | 蜜桃丰满熟妇av无码区不卡 | 国产国语对白又又粗又大又爽 | 国产高清视频无码在线 | 黄污网站在线观看免费在线 | 三亚三黄三色AAA毛片 | 色综合天天综合网国产成人网 | 久久久久久久久一级二级三级桃艳 | 丰满人妻熟女aⅴ中文字幕 又大又粗又爽18禁免费看 | 麻豆一区二区三区四区 | 91精品人妻一区二区三区蜜桃 | 三级片在线播放国产三区 | 国产亲子乱婬一级A片 | 韩国黑寡妇一级毛片 | 国产白丝袜美女久久久久 | 日日夜夜免费精品视频 | 边洗澡边被躁BD在线看 | 亚洲AV无码成人精品区国产 | 免费无码婬片A片AAA日记 | AV-区二区在线观看 无码一区二区三区在线 | 精品久久人人爽人人玩人人妻 | 欧美最猛做爰777777 | 五十路熟妇高熟无码在线观看 | 好爽好大久久久级婬片毛片 |