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Rabbit Anti-GABRA5/APC Conjugated antibody (bs-6708R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-6708R-APC
英文名稱 Rabbit Anti-GABRA5/APC Conjugated antibody
中文名稱 APC標記的γ1氨基丁酸受體α5/GABRα5抗體
別    名 GBRA5_HUMAN; GAA 5; GAA5; GABRA 5; GABRA5; Gamma aminobutyric acid GABA A receptor alpha 5; Gamma aminobutyric acid GABA A receptor alpha 5 precursor; Gamma aminobutyric acid receptor alpha 5 subunit precursor GABA A receptor.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, )
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 47kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GABRA5
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non coding first exons have been described.

Function:
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

Subunit:
Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.

Subcellular Location:
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA5 sub-subfamily.

Database links:

Entrez Gene: 523515 Cow

Entrez Gene: 2558 Human

Entrez Gene: 110886 Mouse

Entrez Gene: 29707 Rat

Omim: 137142 Human

SwissProt: Q08E50 Cow

SwissProt: P31644 Human

SwissProt: Q8BHJ7 Mouse

SwissProt: P19969 Rat

Unigene: 24969 Human

Unigene: 273114 Mouse

Unigene: 10368 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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