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Rabbit Anti-TXNDC11/PE Conjugated antibody (bs-11439R-PE)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-11439R-PE
英文名稱 Rabbit Anti-TXNDC11/PE Conjugated antibody
中文名稱 PE標記的硫氧還蛋白11抗體
別    名 EF-hand-binding protein 1; EFP1; RGD1307538; Thioredoxin domain-containing protein 11; TXD11_HUMAN; TXNDC11; 2810408E11Rik; AI427833.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細胞生物  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 110kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TXNDC11
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.

Function:
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.

Subunit:
Interacts with the cytoplasmic part of DUOX1 and DUOX2. Interacts with TPO and CYBA.

Subcellular Location:
Endoplasmic reticulum membrane.

Tissue Specificity:
Widely expressed at low level. Expressed at higher level in thyroid and prostate.

Similarity:
Belongs to the protein disulfide isomerase family.
Contains 2 thioredoxin domains.

Database links:

Entrez Gene: 490003 Dog

Entrez Gene: 100056118 Horse

Entrez Gene: 51061 Human

SwissProt: Q6PKC3 Human

Unigene: 313847 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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