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Rabbit Anti-PFKFB3/PFK2/RBITC Conjugated antibody (bs-3528R-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3528R-RBITC
英文名稱 Rabbit Anti-PFKFB3/PFK2/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的果糖-2,6-二磷酸酶3/磷酸果糖激酶2抗體
別    名 PFK2; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; 6PF-2-K/Fru-2,6-P2ase 3; PFK/FBPase 3; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; Renal carcinoma antigen NY-REN-56; iPFK-2; 6-phosphofructo-2-kinase; Fructose-2,6-bisphosphatase; F263_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  信號轉導  轉錄調節(jié)因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat,  (predicted: Pig, Cow, Horse, Rabbit, Guinea Pig, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PFKFB3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]

Function:
Synthesis and degradation of fructose 2,6-bisphosphate.

Tissue Specificity:
Ubiquitous.

Similarity:
In the C-terminal section; belongs to the phosphoglycerate mutase family.

Database links:

Entrez Gene: 5209 Human

Entrez Gene: 170768 Mouse

Entrez Gene: 24640 Rat

Omim: 605319 Human

SwissProt: Q16875 Human

SwissProt: P25114 Rat

Unigene: 444304 Human

Unigene: 44844 Rat




Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

IPFK2是糖酵解的一種重要酶,廣泛存在于各種生物細胞中。由于該酶對調控糖酵解通路的重要作用.
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