產(chǎn)品編號(hào) | bs-3576R-Cy5.5 |
英文名稱 | Rabbit Anti-DTSF/HB EGF/Cy5.5 Conjugated antibody |
中文名稱 | Cy5.5標(biāo)記的肝素結(jié)合性表皮生長因子抗體 |
別 名 | HB EGF; Diphtheria toxin receptor; DT R; DT-R; DTR; DTS; DTSF; HB-EGF; HBEGF; HBEGF_HUMAN; HEGFL; heparin binding EGF like growth factor; Heparin binding epidermal growth factor; Heparin binding epidermal growth factor like growth factor; Heparin-binding EGF-like growth factor; Proheparin binding EGF like growth factor. |
規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
說 明 書 | 100ul |
研究領(lǐng)域 | 腫瘤 心血管 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 生長因子和激素 血管內(nèi)皮細(xì)胞 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 21kDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human HB-EGF |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a 22kDa O-glycosylated protein that is a potent mitogen and chemoattractant for vascular smooth muscle cells, fibroblasts and epithelial cells but not endothelial cells. The natural protein has an apparent molecular mass of 19-23 kDa and exists in multiple forms as a result of heterogeneous O-glycosylation and/or Nterminal truncation. HB-EGF is synthesized as a membrane-anchored precursor(proHB-EGF) that is proteolytically cleaved to release the soluble mature growth factor. The two forms are active as juxtacrine and paracrine/autocrine growth factors respectively.HB-EGF activates two EGF receptor subtypes, HER1/ErbB1 and HER4 and binds to heparan sulfate proteoglycan. Function: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor. Subunit: Interacts with FBLN1. Interacts with EGFR and ERBB4. Subcellular Location: Heparin-binding EGF-like growth factor: Secreted, extracellular space. Note=Mature HB-EGF is released into the extracellular space and probably binds to a receptor. Proheparin-binding EGF-like growth factor: Cell membrane; Single-pass type I membrane protein. Post-translational modifications: Several N-termini have been identified by direct sequencing. The forms with N-termini 63, 73 and 74 have been tested and found to be biologically active. O-glycosylated with core 1 or possibly core 8 glycans. Thr-47 is a minor glycosylation site compared to Thr-44. Similarity: Contains 1 EGF-like domain. Database links: Entrez Gene: 1839 Human Omim: 126150 Human SwissProt: Q99075 Human Unigene: 799 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 国产人妻 精品无码蜜汁 | 蜜桃传媒第1页-葡萄Av | 真实人妻互换毛片视频 | 91久久人澡人人添人人爽 | 亚洲无码精品一区 | 人妻人人澡人人添人人爽视频 | 台湾成人做爰A片 | 最好看的2018免费观看在线 | 91精品久久久久 | 亚洲成人AV有码一区 | 欧洲精品无码一区二区 | 17c.com少妇喷水 | 青青青的成人免费视 | 近親相姦交尾六十五路 | 奶大灬大灬大灬大灬硬灬爽灬 | 亚洲无码中文字幕在线观看 | 黑人又粗又大A片免费看 | 成人免费无码婬片在线 | 国产又爽又大又黄A片色戒一 | 美女口交吞精视频 | 一级α一级a爱片免费观看 人人操人人摸人人舔人人肏 | 国产性猛交╳XXX乱大交视频 | 99精品久久毛片A片 国产精品无码久久久久 | 57pao国产成永久免费视频 | 亚洲精品乱码爱爱操麻豆 | 成人做爰A片免费看视频 | 欧美人与性动交α欧美精品 | 色欲av无码一区二区人妻 | 欧美人妻www无码国产黄 | 国产精品1区2区3区 麻豆视频一区二区三区 | 少妇被黑人猛进无码视频 | 奶水旺盛的哺乳人妻AV | 东京热成人A片观看 | 国产一级婬片A片AAA蜜臂 | 国产老熟女做爰毛片A | 国产承认视频免费观看 | 影音先锋AV啪啪资源 | 少妇无码又大又粗又深免小说 | 国产成人91亚洲精品无码观看 | 国产成人精品麻豆传奇 |