產(chǎn)品編號(hào) | bs-0098R-BF647 |
英文名稱 | Rabbit Anti-GIP/BF647 Conjugated antibody |
中文名稱 | BF647標(biāo)記的胃泌素抑制肽抗體 |
別 名 | Gastric Inhibitory polypeptide; Gastric inhibitory polypeptide precursor; GIP; Glucose dependent insulinotropic polypeptide; Gastric Inhibitory Peptide; GIP_HUMAN; Glucose-dependent insulinotropic polypeptide; Incretin hormone. |
規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
說(shuō) 明 書(shū) | 100ul |
研究領(lǐng)域 | 信號(hào)轉(zhuǎn)導(dǎo) 生長(zhǎng)因子和激素 轉(zhuǎn)錄調(diào)節(jié)因子 糖尿病 |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, (predicted: Human, Rat, Pig, Cow, ) |
產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 5/17kDakDa |
性 狀 | Lyophilized or Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human GIP |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: GIP (Gastric Inhibitory polypeptide ) belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. Mature GIP is a highly conserved 42 amino acid polypeptide belonging to the glucagon family. GIP is highly expressed as a pre-pro-protein in the duodenum and the jejunum. The mature secreted polypeptide acts as a potent stimulator of insulin secretion and a poor inhibitor of gastric acid secretion. Function: Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion. Subcellular Location: Secreted. Similarity: Belongs to the glucagon family. Database links: Entrez Gene: 2695 Human Omim: 137240 Human SwissProt: P09681 Human Unigene: 1454 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胃泌素抑制肽(GIP)是胃腸道的一種由42個(gè)氨基酸組成的多肽激素,又稱為葡萄糖依賴性促胰島素多肽(glucose-dependent insulinotropic peptide,GIP)他強(qiáng)烈抑制胃分泌和運(yùn)動(dòng),也可調(diào)節(jié)胰島素的釋放。GIP屬于Glucagon家族成員。 |
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