| 產(chǎn)品編號(hào) | bs-1162R-BF488 |
| 英文名稱(chēng) | Rabbit Anti-CXCL2/GRO Beta/BF488 Conjugated antibody |
| 中文名稱(chēng) | BF488標(biāo)記的巨噬細(xì)胞炎癥蛋白2（ GRＯβ）抗體 |
| 別 名 | C-X-C motif chemokine 2; Chemokine (C X C motif) ligand 2; Chemokine, CXC motif, ligand 2; CINC 2a; CINC2a; CINC3; CXC chemokine; CXCL 2; CXCL2; MIP2; MIP 2; MIP-2; Cytokine-induced neutrophil chemoattractant 3; GRO 2; GRO b; GRO protein, beta; Gro-beta; GRO2; GRO2 oncogene; GROb; GRObeta; GRO Beta; Growth regulated protein beta; GROX; Macrophage inflammatory protein 2 alpha; Macrophage inflammatory protein 2; Melanoma growth stimulatory activity beta; MGSA b; MGSA beta; MGSAbeta; MIP 2; MIP 2a; MIP2 alpha; MIP2; MIP2A; MIP2alpha; SCYB 2; Scyb; SCYB2; Small inducible cytokine subfamily B, member 2. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, Rat, (predicted: Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 12kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MIP2 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: GRO beta is a member of the CXC, or chemokine class. It contains the ELR domain immediately preceding the first cysteine residue near the amino terminus. Other chemokines in this group include IL8, GRO alpha/beta/gamma, mouse KC, ENA78, GCP2, PBP/CTAPIII/beta TG/NAP2. These chemokines act primarily on neutrophils as chemoattractants and activators, including neutrophil degradation with release of myloperoxidase and other enzymes. GRO beta was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. GRO beta is an approximately 8 kDa polypeptide of 73 amino acids. The precursor form of GRO beta consists of 100 amino acids. To generate the mature GRO beta, the precursor cleaves its amino terminal 27 amino acids. GRO beta shows 60% amino acid homology to human GRO alpha and GRO gamma. Function: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. Subcellular Location: Secreted. Post-translational modifications: The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells. Similarity: Belongs to the intercrine alpha (chemokine CxC) family. Database links: Entrez Gene: 2920 Human Entrez Gene: 20310 Mouse SwissProt: P19875 Human SwissProt: P10889 Mouse Unigene: 75765 Human Unigene: 10230 Rat Omim: 139110 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
