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Rabbit Anti-SEC14 like protein 2/Gold Conjugated antibody (bs-7575R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-7575R-Gold
英文名稱 Rabbit Anti-SEC14 like protein 2/Gold Conjugated antibody
中文名稱 膠體金標(biāo)記的SEC14樣蛋白2抗體
別    名 Alpha tocopherol associated protein; Alpha-tocopherol-associated protein; C22orf6; hTAP; S14L2_HUMAN; SEC14 (S. cerevisiae) like 2; SEC14 like 2 (S. cerevisiae); SEC14 like protein 2; SEC14-like protein 2; Sec14l2; SPF; Squalene transfer protein; Supernatant protein factor; TAP; TAP1; tocopherol-associated protein; hide.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 心血管  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 46kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SEC14 like protein 2 (101-140aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.
Tissue specificity: Widely expressed. Strong expression in liver, brain and prostate.

Function:
Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.

Subunit:
Monomer

Subcellular Location:
Cytoplasm. Nucleus. Note=Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha-tocopherol.

Tissue Specificity:
Widely expressed. Strong expression in liver, brain and prostate.

Similarity:
Contains 1 CRAL-TRIO domain.
Contains 1 GOLD domain. [SEQUENCE CAUTION] Sequence=BAA86500.2; Type=Erroneous initiation.

Database links:
UniProtKB/Swiss-Prot: O76054.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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