| 產(chǎn)品編號 | bs-7077R-BF488 |
| 英文名稱 | Rabbit Anti-RERE/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的肌萎縮相關(guān)蛋白1抗體 |
| 別 名 | ARG; arginine glutamic acid dipeptide (RE) repeats; arginine glutamic acid dipeptide repeats; Arginine glutamic acid dipeptide repeats protein; Arginine-glutamic acid dipeptide repeats protein; ARGININE-GLUTAMIC ACID REPEATS-ENCODING GENE; ARP; ATN1L; Atr2; atrophin 1 like; Atrophin 1 like protein; Atrophin 1 related protein; atrophin 2; atrophin related protein; ATROPHIN-1-ASSOCIATED PROTEIN; Atrophin-1-like protein; Atrophin-1-related protein; atrophin-2; ATROPHIN-RELATED PROTEIN; DNB1; Rere; RERE_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 172kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RERE |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: FunctionPlays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. Function: Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. Subunit: Interacts with HDAC1 (By similarity). Interacts with ATN1. Interaction with ATN1 is improved when the poly-Gln region of ATN1 is extended. Interacts with FAT1. Subcellular Location: Nucleus. Note=Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs. Tissue Specificity: Widely expressed. Expressed in tumor cell lines. DISEASE: Note=A chromosomal aberration involving RERE is found in the neuroblastoma cell line NGP. Translocation t(1;15)(p36.2;q24). Similarity: Contains 1 BAH domain. Contains 1 ELM2 domain. Contains 1 GATA-type zinc finger. Contains 1 SANT domain. Database links: UniProtKB/Swiss-Prot: Q9P2R6.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
